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To study an environmental or biological solution, it is essential to separate its constituents. In this study, a 3D-deformable dynamic microfilter was developed to selectively separate the target substance from a solution. This microfilter is a fine metallic nickel structure fabricated using photolithography and electroplating techniques. It is gold-coated across its entire surface with multiple slits of 10–20 μm in width. Its two-dimensional shape is deformed into a three-dimensional shape when used for fluid separation due to hydrodynamic forces. By adjusting the pressure applied to the microfilter, the size of the gap created by deformation can be changed. To effectively isolate the target substance, the relationship between the solution flow rate and the extent of microfilter deformation was investigated. The filtration experiments demonstrated the microfilter’s ability to isolate the target substance with elastic deformation without undergoing plastic deformation. Additionally, modification of the microfilter surface with nucleic acid aptamers resulted in the selective isolation of the target cell, which further demonstrates the potential application of microfilters in the isolation of specific components of heterogeneous solutions.  相似文献   
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To cope with ambiguous and/or underspecified queries, search result diversification (SRD) is a key technique that has attracted a lot of attention. This paper focuses on implicit SRD, where the subtopics underlying a query are unknown. Many existing methods appeal to the greedy strategy for generating diversified results. A common practice is using a heuristic criterion for making the locally optimal choice at each round. As a result, it is difficult to know whether the failures are caused by the optimization criterion or the setting of parameters. Different from previous studies, we formulate implicit SRD as a process of selecting and ranking k exemplar documents through integer linear programming (ILP). The key idea is that: for a specific query, we expect to maximize the overall relevance of the k exemplar documents. Meanwhile, we wish to maximize the representativeness of the selected exemplar documents with respect to the non-selected documents. Intuitively, if the selected exemplar documents concisely represent the entire set of documents, the novelty and diversity will naturally arise. Moreover, we propose two approaches ILP4ID (Integer Linear Programming for Implicit SRD) and AP4ID (Affinity Propagation for Implicit SRD) for solving the proposed formulation of implicit SRD. In particular, ILP4ID appeals to the strategy of bound-and-branch and is able to obtain the optimal solution. AP4ID being an approximate method transforms the target problem as a maximum-a-posteriori inference problem, and the message passing algorithm is adopted to find the solution. Furthermore, we investigate the differences and connections between the proposed models and prior models by casting them as different variants of the cluster-based paradigm for implicit SRD. To validate the effectiveness and efficiency of the proposed approaches, we conduct a series of experiments on four benchmark TREC diversity collections. The experimental results demonstrate that: (1) The proposed methods, especially ILP4ID, can achieve substantially improved performance over the state-of-the-art unsupervised methods for implicit SRD. (2) The initial runs, the number of input documents, query types, the ways of computing document similarity, the pre-defined cluster number and the optimization algorithm significantly affect the performance of diversification models. Careful examinations of these factors are highly recommended in the development of implicit SRD methods. Based on the in-depth study of different types of methods for implicit SRD, we provide additional insight into the cluster-based paradigm for implicit SRD. In particular, how the methods relying on greedy strategies impact the performance of implicit SRD, and how a particular diversification model should be fine-tuned.  相似文献   
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The presentation of search results on the web has been dominated by the textual form of document representation. On the other hand, the document’s visual aspects such as the layout, colour scheme, or presence of images have been studied in a limited context with regard to their effectiveness of search result presentation. This article presents a comparative evaluation of textual and visual forms of document representation as additional components of document surrogates. A total of 24 people were recruited for our task-based user study. The experimental results suggest that an increased level of document representation available in the search results can facilitate users’ interaction with a search interface. The results also suggest that the two forms of additional representations are likely beneficial to users’ information searching process in different contexts.  相似文献   
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利用最新的GRAIL月球重力数据和LRO地形数据,计算重力/地形导纳及其相关性。结果表明,最新的测月数据能够在球谐系数达到500阶的时候依然保持比较高的相关性,精度得到很大的提高。全月重力/地形导纳在50阶以下(波长大于~220 km),之后迅速增加,维持在110 mgal/km附近。利用Gauss-Newton迭代法计算得到全月弹性平均厚度Te=11.7 km,表明很有可能月球地形在月球早期就已经形成。  相似文献   
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We clarify how individuals actively interact with socio-cultural contexts to attain regular employment in Japan. Based on a large sample (N = 3,512) of part-time employed and unemployed college graduates (23–39 years old), we found that: Career decision making self-efficacy predicted job search; a lack of both hope and fulfillment motivated job search, while having hope promoted it; wishing for perfect vocation and being free from both inclination towards personal interests and passivity motivated job search. Clients’ desire for “a perfect vocation,” should not necessarily be considered as a career barrier but, perhaps, rather as an asset for motivating job search. Counselors should seek to better understand the influence of clients’ socio-cultural contexts on their career attitudes.  相似文献   
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